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MicroRNA regulation of unfolded protein response transcription factor XBP1 in the progression of cardiac hypertrophy and heart failure in vivo

BACKGROUND: XBP1 is a key transcription factor of the unfolded protein response in mammalian cells, which is involved in several cardiovascular pathological progression including cardiac hypertrophy and myocardial infarction, but its expression trend, function and upstream regulate mechanism in the...

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Detalles Bibliográficos
Autores principales: Duan, Quanlu, Chen, Chen, Yang, Lei, Li, Ni, Gong, Wei, Li, Sheng, Wang, Dao Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647486/
https://www.ncbi.nlm.nih.gov/pubmed/26572862
http://dx.doi.org/10.1186/s12967-015-0725-4