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Differential p16/INK4A cyclin-dependent kinase inhibitor expression correlates with chemotherapy efficacy in a cohort of 88 malignant pleural mesothelioma patients

BACKGROUND: Malignant pleural mesothelioma (MPM) is a rare and essentially incurable malignancy most often linked with occupational exposure to asbestos fibres. In common with other malignancies, the development and progression of MPM is associated with extensive dysregulation of cell cycle checkpoi...

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Detalles Bibliográficos
Autores principales: Jennings, C J, Murer, B, O'Grady, A, Hearn, L M, Harvey, B J, Kay, E W, Thomas, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647524/
https://www.ncbi.nlm.nih.gov/pubmed/26057448
http://dx.doi.org/10.1038/bjc.2015.187