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Silencio/CG9754 connects the Piwi–piRNA complex to the cellular heterochromatin machinery

The repression of transposable elements in eukaryotes often involves their transcriptional silencing via targeted chromatin modifications. In animal gonads, nuclear Argonaute proteins of the PIWI clade complexed with small guide RNAs (piRNAs) serve as sequence specificity determinants in this proces...

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Detalles Bibliográficos
Autores principales: Sienski, Grzegorz, Batki, Julia, Senti, Kirsten-André, Dönertas, Derya, Tirian, Laszlo, Meixner, Katharina, Brennecke, Julius
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647559/
https://www.ncbi.nlm.nih.gov/pubmed/26494711
http://dx.doi.org/10.1101/gad.271908.115