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Population genetic structure and natural selection of apical membrane antigen-1 in Plasmodium vivax Korean isolates

BACKGROUND: Plasmodium vivax apical membrane antigen-1 (PvAMA-1) is a leading candidate antigen for blood stage malaria vaccine. However, antigenic variation is a major obstacle in the development of an effective vaccine based on this antigen. In this study, the genetic structure and the effect of n...

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Detalles Bibliográficos
Autores principales: Kang, Jung-Mi, Lee, Jinyoung, Cho, Pyo-Yun, Moon, Sung-Ung, Ju, Hye-Lim, Ahn, Seong Kyu, Sohn, Woon-Mok, Lee, Hyeong-Woo, Kim, Tong-Soo, Na, Byoung-Kuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647566/
https://www.ncbi.nlm.nih.gov/pubmed/26572984
http://dx.doi.org/10.1186/s12936-015-0942-6