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Population genetic structure and natural selection of apical membrane antigen-1 in Plasmodium vivax Korean isolates
BACKGROUND: Plasmodium vivax apical membrane antigen-1 (PvAMA-1) is a leading candidate antigen for blood stage malaria vaccine. However, antigenic variation is a major obstacle in the development of an effective vaccine based on this antigen. In this study, the genetic structure and the effect of n...
Autores principales: | Kang, Jung-Mi, Lee, Jinyoung, Cho, Pyo-Yun, Moon, Sung-Ung, Ju, Hye-Lim, Ahn, Seong Kyu, Sohn, Woon-Mok, Lee, Hyeong-Woo, Kim, Tong-Soo, Na, Byoung-Kuk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647566/ https://www.ncbi.nlm.nih.gov/pubmed/26572984 http://dx.doi.org/10.1186/s12936-015-0942-6 |
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