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Integrated genomics approach to identify biologically relevant alterations in fewer samples

BACKGROUND: Several statistical tools have been developed to identify genes mutated at rates significantly higher than background, indicative of positive selection, involving large sample cohort studies. However, studies involving smaller sample sizes are inherently restrictive due to their limited...

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Detalles Bibliográficos
Autores principales: Chandrani, Pratik, Upadhyay, Pawan, Iyer, Prajish, Tanna, Mayur, Shetty, Madhur, Raghuram, Gorantala Venkata, Oak, Ninad, Singh, Ankita, Chaubal, Rohan, Ramteke, Manoj, Gupta, Sudeep, Dutt, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647579/
https://www.ncbi.nlm.nih.gov/pubmed/26572163
http://dx.doi.org/10.1186/s12864-015-2138-4