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Integrated genomics approach to identify biologically relevant alterations in fewer samples
BACKGROUND: Several statistical tools have been developed to identify genes mutated at rates significantly higher than background, indicative of positive selection, involving large sample cohort studies. However, studies involving smaller sample sizes are inherently restrictive due to their limited...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647579/ https://www.ncbi.nlm.nih.gov/pubmed/26572163 http://dx.doi.org/10.1186/s12864-015-2138-4 |