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Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits

BACKGROUND: Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by impairment in social communication/interaction and inflexible/repetitive behavior. Several lines of evidence support genetic factors as a predominant cause of ASD. Among those autism susceptibility...

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Detalles Bibliográficos
Autores principales: He, Xin, Thacker, Stetson, Romigh, Todd, Yu, Qi, Frazier, Thomas W., Eng, Charis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647625/
https://www.ncbi.nlm.nih.gov/pubmed/26579216
http://dx.doi.org/10.1186/s13229-015-0056-6