Targeted amplification for enhanced detection of biothreat agents by next-generation sequencing

BACKGROUND: Historically, identification of causal agents of disease has relied heavily on the ability to culture the organism in the laboratory and/or the use of pathogen-specific antibodies or sequence-based probes. However, these methods can be limiting: Even highly sensitive PCR-based assays mus...

Descripción completa

Detalles Bibliográficos
Autores principales: Gardner, Shea N., Frey, Kenneth G., Redden, Cassie L., Thissen, James B., Allen, Jonathan E., Allred, Adam F., Dyer, Matthew D., Mokashi, Vishwesh P., Slezak, Tom R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647626/
https://www.ncbi.nlm.nih.gov/pubmed/26572552
http://dx.doi.org/10.1186/s13104-015-1530-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647626/
https://www.ncbi.nlm.nih.gov/pubmed/26572552
http://dx.doi.org/10.1186/s13104-015-1530-0

Ejemplares similares