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Targeted amplification for enhanced detection of biothreat agents by next-generation sequencing
BACKGROUND: Historically, identification of causal agents of disease has relied heavily on the ability to culture the organism in the laboratory and/or the use of pathogen-specific antibodies or sequence-based probes. However, these methods can be limiting: Even highly sensitive PCR-based assays mus...
Autores principales: | Gardner, Shea N., Frey, Kenneth G., Redden, Cassie L., Thissen, James B., Allen, Jonathan E., Allred, Adam F., Dyer, Matthew D., Mokashi, Vishwesh P., Slezak, Tom R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647626/ https://www.ncbi.nlm.nih.gov/pubmed/26572552 http://dx.doi.org/10.1186/s13104-015-1530-0 |
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