Combination of sorafenib and gadolinium chloride (GdCl3) attenuates dimethylnitrosamine(DMN)-induced liver fibrosis in rats

BACKGROUND/AIMS: Liver sinusoidal endothelial cells (SECs), hepatic stellate cells (HSCs) and Kupffer cells (KCs) are involved in the development of liver fibrosis and represent a potential therapeutic target. The therapeutic effects on liver fibrosis of sorafenib, a multiple tyrosine kinase inhibit...

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Detalles Bibliográficos
Autores principales: Liu, Cheng, Yang, Zongguo, Wang, Lei, Lu, Yunfei, Tang, Bozong, Miao, Hui, Xu, Qingnian, Chen, Xiaorong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647665/
https://www.ncbi.nlm.nih.gov/pubmed/26572488
http://dx.doi.org/10.1186/s12876-015-0380-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647665/
https://www.ncbi.nlm.nih.gov/pubmed/26572488
http://dx.doi.org/10.1186/s12876-015-0380-5

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