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Combination of sorafenib and gadolinium chloride (GdCl3) attenuates dimethylnitrosamine(DMN)-induced liver fibrosis in rats
BACKGROUND/AIMS: Liver sinusoidal endothelial cells (SECs), hepatic stellate cells (HSCs) and Kupffer cells (KCs) are involved in the development of liver fibrosis and represent a potential therapeutic target. The therapeutic effects on liver fibrosis of sorafenib, a multiple tyrosine kinase inhibit...
Autores principales: | Liu, Cheng, Yang, Zongguo, Wang, Lei, Lu, Yunfei, Tang, Bozong, Miao, Hui, Xu, Qingnian, Chen, Xiaorong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647665/ https://www.ncbi.nlm.nih.gov/pubmed/26572488 http://dx.doi.org/10.1186/s12876-015-0380-5 |
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