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Dormant non-culturable Mycobacterium tuberculosis retains stable low-abundant mRNA

BACKGROUND: Dormant Mycobacterium tuberculosis bacilli are believed to play an important role in latent tuberculosis infection. Previously, we have demonstrated that cultivation of M. tuberculosis in K(+)-deficient medium resulted in generation of dormant cells. These bacilli were non-culturable on...

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Detalles Bibliográficos
Autores principales: Ignatov, Dmitriy V., Salina, Elena G., Fursov, Mikhail V., Skvortsov, Timofey A., Azhikina, Tatyana L., Kaprelyants, Arseny S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647672/
https://www.ncbi.nlm.nih.gov/pubmed/26573524
http://dx.doi.org/10.1186/s12864-015-2197-6