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Clinical and genomic analysis of a randomised phase II study evaluating anastrozole and fulvestrant in postmenopausal patients treated for large operable or locally advanced hormone-receptor-positive breast cancer

BACKGROUND: The aim of this study was to assess the efficacy of neoadjuvant anastrozole and fulvestrant treatment of large operable or locally advanced hormone-receptor-positive breast cancer not eligible for initial breast-conserving surgery, and to identify genomic changes occurring after treatmen...

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Detalles Bibliográficos
Autores principales: Quenel-Tueux, Nathalie, Debled, Marc, Rudewicz, Justine, MacGrogan, Gaetan, Pulido, Marina, Mauriac, Louis, Dalenc, Florence, Bachelot, Thomas, Lortal, Barbara, Breton-Callu, Christelle, Madranges, Nicolas, de Lara, Christine Tunon, Fournier, Marion, Bonnefoi, Hervé, Soueidan, Hayssam, Nikolski, Macha, Gros, Audrey, Daly, Catherine, Wood, Henry, Rabbitts, Pamela, Iggo, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647692/
https://www.ncbi.nlm.nih.gov/pubmed/26171933
http://dx.doi.org/10.1038/bjc.2015.247