Cargando…
Clinical and genomic analysis of a randomised phase II study evaluating anastrozole and fulvestrant in postmenopausal patients treated for large operable or locally advanced hormone-receptor-positive breast cancer
BACKGROUND: The aim of this study was to assess the efficacy of neoadjuvant anastrozole and fulvestrant treatment of large operable or locally advanced hormone-receptor-positive breast cancer not eligible for initial breast-conserving surgery, and to identify genomic changes occurring after treatmen...
Autores principales: | Quenel-Tueux, Nathalie, Debled, Marc, Rudewicz, Justine, MacGrogan, Gaetan, Pulido, Marina, Mauriac, Louis, Dalenc, Florence, Bachelot, Thomas, Lortal, Barbara, Breton-Callu, Christelle, Madranges, Nicolas, de Lara, Christine Tunon, Fournier, Marion, Bonnefoi, Hervé, Soueidan, Hayssam, Nikolski, Macha, Gros, Audrey, Daly, Catherine, Wood, Henry, Rabbitts, Pamela, Iggo, Richard |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647692/ https://www.ncbi.nlm.nih.gov/pubmed/26171933 http://dx.doi.org/10.1038/bjc.2015.247 |
Ejemplares similares
-
MICADo – Looking for Mutations in Targeted PacBio Cancer Data: An Alignment-Free Method
por: Rudewicz, Justine, et al.
Publicado: (2016) -
Predictive factors of 5-year relapse-free survival in HR+/HER2- breast cancer patients treated with neoadjuvant endocrine therapy: pooled analysis of two phase 2 trials
por: Lerebours, Florence, et al.
Publicado: (2020) -
Identification of conserved gene clusters in multiple genomes based on synteny and homology
por: Sarkar, Anasua, et al.
Publicado: (2011) -
Finding and identifying the viral needle in the metagenomic haystack: trends and challenges
por: Soueidan, Hayssam, et al.
Publicado: (2015) -
A randomized trial to assess the biological activity of short-term (pre-surgical) fulvestrant 500 mg plus anastrozole versus fulvestrant 500 mg alone or anastrozole alone on primary breast cancer
por: Robertson, John FR, et al.
Publicado: (2013)