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Quantitative framework for ordered degradation of APC/C substrates

BACKGROUND: During cell-cycle progression, substrates of a single master regulatory enzyme can be modified in a specific order. Here, we used experimental and computational approaches to dissect the quantitative mechanisms underlying the ordered degradation of the substrates of the ubiquitin ligase...

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Detalles Bibliográficos
Autores principales:	Lu, Dan, Girard, Juliet R., Li, Weihan, Mizrak, Arda, Morgan, David O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647693/ https://www.ncbi.nlm.nih.gov/pubmed/26573515 http://dx.doi.org/10.1186/s12915-015-0205-6

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