Dichotomizing partial compliance and increased participant burden in factorial designs: the performance of four noncompliance methods

BACKGROUND: Noncompliance to treatment assignment is an inevitable occurrence in randomized clinical trials (RCTs). Intention to treat (ITT) is generally considered the best method for addressing noncompliance in RCTs. Alternatives to ITT exist, including per protocol (PP), as treated (AT), and inst...

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Detalles Bibliográficos
Autores principales: Merrill, Peter D., McClure, Leslie A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647702/
https://www.ncbi.nlm.nih.gov/pubmed/26573840
http://dx.doi.org/10.1186/s13063-015-1044-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647702/
https://www.ncbi.nlm.nih.gov/pubmed/26573840
http://dx.doi.org/10.1186/s13063-015-1044-z

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