Cargando…
Dichotomizing partial compliance and increased participant burden in factorial designs: the performance of four noncompliance methods
BACKGROUND: Noncompliance to treatment assignment is an inevitable occurrence in randomized clinical trials (RCTs). Intention to treat (ITT) is generally considered the best method for addressing noncompliance in RCTs. Alternatives to ITT exist, including per protocol (PP), as treated (AT), and inst...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647702/ https://www.ncbi.nlm.nih.gov/pubmed/26573840 http://dx.doi.org/10.1186/s13063-015-1044-z |