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Generalizing boundaries for triangular designs, and efficacy estimation at extended follow-ups

BACKGROUND: Visceral leishmaniasis (VL) is a parasitic disease transmitted by sandflies and is fatal if left untreated. Phase II trials of new treatment regimens for VL are primarily carried out to evaluate safety and efficacy, while pharmacokinetic data are also important to inform future combinati...

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Detalles Bibliográficos
Autores principales: Allison, Annabel, Edwards, Tansy, Omollo, Raymond, Alves, Fabiana, Magirr, Dominic, E. Alexander, Neal D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647805/
https://www.ncbi.nlm.nih.gov/pubmed/26573827
http://dx.doi.org/10.1186/s13063-015-1018-1