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Caffeine reduces hepatic lipid accumulation through regulation of lipogenesis and ER stress in zebrafish larvae

BACKGROUND: Caffeine, the main component of coffee, has showed its protective effect on non-alcoholic fatty liver disease (NAFLD) in many studies. However, the hepatoprotection of caffeine and its mechanisms in zebrafish were unexplored. Thus, this study’s intentions are to establish a NAFLD model o...

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Detalles Bibliográficos
Autores principales: Zheng, Xinchun, Dai, Wencong, Chen, Xiaohui, Wang, Kunyuan, Zhang, Wenqing, Liu, Li, Hou, Jinlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647812/
https://www.ncbi.nlm.nih.gov/pubmed/26572131
http://dx.doi.org/10.1186/s12929-015-0206-3