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Loss of FOXO1 promotes gastric tumour growth and metastasis through upregulation of human epidermal growth factor receptor 2/neu expression

BACKGROUND: The biological significance of FOXO1, a member of the forkhead box O transcription factor family, in gastric cancer (GC) remains unclear. The present study provides direct evidence of the role of FOXO1 in tumour growth and metastasis of GC in relation to human epidermal growth factor rec...

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Detalles Bibliográficos
Autores principales: Ko, Young San, Cho, Sung Jin, Park, Jinju, Kim, Younghoon, Choi, Yong Joon, Pyo, Jung-Soo, Jang, Bo Gun, Park, Jong-Wan, Kim, Woo Ho, Lee, Byung Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647872/
https://www.ncbi.nlm.nih.gov/pubmed/26448177
http://dx.doi.org/10.1038/bjc.2015.273