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Loss of FOXO1 promotes gastric tumour growth and metastasis through upregulation of human epidermal growth factor receptor 2/neu expression
BACKGROUND: The biological significance of FOXO1, a member of the forkhead box O transcription factor family, in gastric cancer (GC) remains unclear. The present study provides direct evidence of the role of FOXO1 in tumour growth and metastasis of GC in relation to human epidermal growth factor rec...
Autores principales: | Ko, Young San, Cho, Sung Jin, Park, Jinju, Kim, Younghoon, Choi, Yong Joon, Pyo, Jung-Soo, Jang, Bo Gun, Park, Jong-Wan, Kim, Woo Ho, Lee, Byung Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647872/ https://www.ncbi.nlm.nih.gov/pubmed/26448177 http://dx.doi.org/10.1038/bjc.2015.273 |
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