Catalytic Nucleophilic Fluorination of Secondary and Tertiary Propargylic Electrophiles with a Copper–N-Heterocyclic Carbene Complex

A catalytic method for the nucleophilic fluorination of propargylic electrophiles is described. Our protocol involves the use of a Cu(NHC) complex as the catalyst and is suitable for the preparation of secondary and tertiary propargylic fluorides without the formation of isomeric fluoroallenes. Prel...

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Detalles Bibliográficos
Autores principales: Cheng, Li-Jie, Cordier, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648036/
https://www.ncbi.nlm.nih.gov/pubmed/26403935
http://dx.doi.org/10.1002/anie.201506882

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648036/
https://www.ncbi.nlm.nih.gov/pubmed/26403935
http://dx.doi.org/10.1002/anie.201506882

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