Stereo- and Chemodivergent NHC-Promoted Functionalisation of Arylalkylketenes with Chloral**

Stereo- and chemodivergent enantioselective reaction pathways are observed upon treatment of alkylarylketenes and trichloroacetaldehyde (chloral) with N-heterocyclic carbenes, giving selectively either β-lactones (up to 88:12 dr, up to 94 % ee) or α-chloroesters (up to 94 % ee). Either 2-arylsubstit...

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Detalles Bibliográficos
Autores principales: Douglas, James J, Churchill, Gwydion, Slawin, Alexandra M Z, Fox, David J, Smith, Andrew D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648049/
https://www.ncbi.nlm.nih.gov/pubmed/26406613
http://dx.doi.org/10.1002/chem.201503308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648049/
https://www.ncbi.nlm.nih.gov/pubmed/26406613
http://dx.doi.org/10.1002/chem.201503308

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