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Phospholipase C-β1 Hypofunction in the Pathogenesis of Schizophrenia

Schizophrenia is a mental disorder that is characterized by various abnormal symptoms. Previous studies indicate decreased expression of phospholipase C-β1 (PLC-β1) in the brains of patients with schizophrenia. PLC-β1-null (PLC-β1(−/−)) mice exhibit multiple endophenotypes of schizophrenia. Furtherm...

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Detalles Bibliográficos
Autores principales: Kim, Seong-Wook, Cho, Taesup, Lee, Sukchan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648068/
https://www.ncbi.nlm.nih.gov/pubmed/26635636
http://dx.doi.org/10.3389/fpsyt.2015.00159