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Combined use of spatial restraint stress and middle cerebral artery occlusion is a novel model of post-stroke depression in mice

Post stroke depression (PSD) is one of the most common complications of ischemic stroke. At present, the underlying mechanisms are unclear, largely because there are no reliable, valid and reproducible animal models of PSD. Here we report a novel animal model of PSD that displays consistent and reli...

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Detalles Bibliográficos
Autores principales: Zhang, Gaocai, Chen, Li, Yang, Lingli, Hua, Xiaodong, Zhou, Beiqun, Miao, Zhigang, Li, Jizhen, Hu, Hua, Namaka, Michael, Kong, Jiming, Xu, Xingshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648085/
https://www.ncbi.nlm.nih.gov/pubmed/26572587
http://dx.doi.org/10.1038/srep16751