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Combined use of spatial restraint stress and middle cerebral artery occlusion is a novel model of post-stroke depression in mice
Post stroke depression (PSD) is one of the most common complications of ischemic stroke. At present, the underlying mechanisms are unclear, largely because there are no reliable, valid and reproducible animal models of PSD. Here we report a novel animal model of PSD that displays consistent and reli...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648085/ https://www.ncbi.nlm.nih.gov/pubmed/26572587 http://dx.doi.org/10.1038/srep16751 |