Insight into 2α-Chloro-2′(2′,6′)-(Di)Halogenopicropodophyllotoxins Reacting with Carboxylic Acids Mediated by BF(3)·Et(2)O

Stereospecific nucleophilic substitution at the C-4α position of 2α-chloro-2′(2′,6′)-(di)halogenopicropodophyllotoxin derivatives with carboxylic acids mediated by BF(3)·Et(2)O was described. Interestingly, this stereoselective products were completely controlled by the reaction time. That is, if th...

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Detalles Bibliográficos
Autores principales: Fan, Lingling, Zhi, Xiaoyan, Che, Zhiping, Xu, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648097/
https://www.ncbi.nlm.nih.gov/pubmed/26573374
http://dx.doi.org/10.1038/srep16285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648097/
https://www.ncbi.nlm.nih.gov/pubmed/26573374
http://dx.doi.org/10.1038/srep16285

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