Cargando…
Insight into 2α-Chloro-2′(2′,6′)-(Di)Halogenopicropodophyllotoxins Reacting with Carboxylic Acids Mediated by BF(3)·Et(2)O
Stereospecific nucleophilic substitution at the C-4α position of 2α-chloro-2′(2′,6′)-(di)halogenopicropodophyllotoxin derivatives with carboxylic acids mediated by BF(3)·Et(2)O was described. Interestingly, this stereoselective products were completely controlled by the reaction time. That is, if th...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648097/ https://www.ncbi.nlm.nih.gov/pubmed/26573374 http://dx.doi.org/10.1038/srep16285 |