Deep Sequencing of the T-cell Receptor Repertoire Demonstrates Polyclonal T-cell Infiltrates in Psoriasis

It is well known that infiltration of pathogenic T-cells plays an important role in psoriasis pathogenesis. However, the antigen specificity of these activated T-cells is relatively unknown. Previous studies using T-cell receptor polymerase chain reaction technology (TCR-PCR) have suggested there ar...

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Detalles Bibliográficos
Autores principales: Harden, Jamie L., Hamm, David, Gulati, Nicholas, Lowes, Michelle A., Krueger, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648215/
https://www.ncbi.nlm.nih.gov/pubmed/26594339
http://dx.doi.org/10.12688/f1000research.6756.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648215/
https://www.ncbi.nlm.nih.gov/pubmed/26594339
http://dx.doi.org/10.12688/f1000research.6756.1

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