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A ChIP on the shoulder? Chromatin immunoprecipitation and validation strategies for ChIP antibodies

Chromatin immunoprecipitation (ChIP) is a technique widely used in the study of epigenetics and transcriptional regulation of gene expression. However, its antibody-centric nature exposes it to similar challenges faced by other antibody-based procedures, of which the most prominent are issues of spe...

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Detalles Bibliográficos
Autores principales: Wardle, Fiona C., Tan, Haihan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648227/
https://www.ncbi.nlm.nih.gov/pubmed/26594335
http://dx.doi.org/10.12688/f1000research.6719.1