Fasting activates macroautophagy in neurons of Alzheimer’s disease mouse model but is insufficient to degrade amyloid-beta

We developed a new technique to observe macroautophagy in the brain in vivo, and examined whether fasting induced macroautophagy in neurons and how the induction was different between Alzheimer’s disease (AD) model and control mice. Lentivirus for EGFP-LC3 injected into the brain successfully visual...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Xigui, Kondo, Kanoh, Motoki, Kazumi, Homma, Hidenori, Okazawa, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648430/
https://www.ncbi.nlm.nih.gov/pubmed/26169250
http://dx.doi.org/10.1038/srep12115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648430/
https://www.ncbi.nlm.nih.gov/pubmed/26169250
http://dx.doi.org/10.1038/srep12115

Ejemplares similares