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MBSTAR: multiple instance learning for predicting specific functional binding sites in microRNA targets

MicroRNA (miRNA) regulates gene expression by binding to specific sites in the 3′untranslated regions of its target genes. Machine learning based miRNA target prediction algorithms first extract a set of features from potential binding sites (PBSs) in the mRNA and then train a classifier to distingu...

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Detalles Bibliográficos
Autores principales: Bandyopadhyay, Sanghamitra, Ghosh, Dip, Mitra, Ramkrishna, Zhao, Zhongming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648438/
https://www.ncbi.nlm.nih.gov/pubmed/25614300
http://dx.doi.org/10.1038/srep08004