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PKCζ Promotes Breast Cancer Invasion by Regulating Expression of E-cadherin and Zonula Occludens-1 (ZO-1) via NFκB-p65

Atypical Protein Kinase C zeta (PKCζ) forms Partitioning-defective (PAR) polarity complex for apico-basal distribution of membrane proteins essential to maintain normal cellular junctional complexes and tissue homeostasis. Consistently, tumor suppressive role of PKCζ has been established for multipl...

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Detalles Bibliográficos
Autores principales: Paul, Arindam, Danley, Marsha, Saha, Biswarup, Tawfik, Ossama, Paul, Soumen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648478/
https://www.ncbi.nlm.nih.gov/pubmed/26218882
http://dx.doi.org/10.1038/srep12520