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Beyond the E-Value: Stratified Statistics for Protein Domain Prediction
E-values have been the dominant statistic for protein sequence analysis for the past two decades: from identifying statistically significant local sequence alignments to evaluating matches to hidden Markov models describing protein domain families. Here we formally show that for “stratified” multipl...
Autores principales: | Ochoa, Alejandro, Storey, John D., Llinás, Manuel, Singh, Mona |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648515/ https://www.ncbi.nlm.nih.gov/pubmed/26575353 http://dx.doi.org/10.1371/journal.pcbi.1004509 |
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