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Iron Chelation Inhibits Osteoclastic Differentiation In Vitro and in Tg2576 Mouse Model of Alzheimer’s Disease

Patients of Alzheimer’s disease (AD) frequently have lower bone mineral density and higher rate of hip fracture. Tg2576, a well characterized AD animal model that ubiquitously express Swedish mutant amyloid precursor protein (APPswe), displays not only AD-relevant neuropathology, but also age-depend...

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Detalles Bibliográficos
Autores principales: Guo, Jun-Peng, Pan, Jin-Xiu, Xiong, Lei, Xia, Wen-Fang, Cui, Shun, Xiong, Wen-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648559/
https://www.ncbi.nlm.nih.gov/pubmed/26575486
http://dx.doi.org/10.1371/journal.pone.0139395