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Incidence and clinical significance of ESR1 mutations in heavily pretreated metastatic breast cancer patients

BACKGROUND: ESR1 mutation has recently emerged as one of the important mechanisms involved in endocrine resistance. The incidence and clinical implication of ESR1 mutation has not been well evaluated in heavily pretreated breast cancer patients. METHODS: We conducted a retrospective review of advanc...

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Detalles Bibliográficos
Autores principales: Niu, Jiaxin, Andres, Grant, Kramer, Kim, Kundranda, Madappa N, Alvarez, Ricardo H, Klimant, Eiko, Parikh, Ankur R, Tan, Bradford, Staren, Edgar D, Markman, Maurie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648593/
https://www.ncbi.nlm.nih.gov/pubmed/26648736
http://dx.doi.org/10.2147/OTT.S92443