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A single-arm Phase II validation study of preventing oxaliplatin-induced hypersensitivity reactions by dexamethasone: the AVOID trial

BACKGROUND: Patients with colorectal cancer treated with oxaliplatin are at risk of hypersensitivity reactions, with the incidence estimated to be 12%–20%. Coinfusion of dexamethasone and oxaliplatin could potentially reduce the incidence of these reactions, but oxaliplatin is reported to be incompa...

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Detalles Bibliográficos
Autores principales: Yoshida, Yoichiro, Hirata, Keiji, Matsuoka, Hiroshi, Iwamoto, Shigeyoshi, Kotaka, Masahito, Fujita, Hideto, Aisu, Naoya, Hoshino, Seiichiro, Kosaka, Takeo, Maeda, Kotaro, Kiyomi, Fumiaki, Yamashita, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648596/
https://www.ncbi.nlm.nih.gov/pubmed/26648694
http://dx.doi.org/10.2147/DDDT.S94901