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Suppression of Hyperactive Immune Responses Protects against Nitrogen Mustard Injury

DNA alkylating agents like nitrogen mustard (NM) are easily absorbed through the skin and exposure to such agents manifest not only in direct cellular death but also in triggering inflammation. We show that toxicity resulting from topical mustard exposure is mediated in part by initiating exaggerate...

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Detalles Bibliográficos
Autores principales: Au, Liemin, Meisch, Jeffrey P, Das, Lopa M, Binko, Amy M, Boxer, Rebecca S, Wen, Amy M, Steinmetz, Nicole F, Lu, Kurt Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648631/
https://www.ncbi.nlm.nih.gov/pubmed/26288355
http://dx.doi.org/10.1038/jid.2015.322