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Mass spectrometry-based ligand binding assays on adenosine A(1) and A(2A) receptors

Conventional methods to measure ligand-receptor binding parameters typically require radiolabeled ligands as probes. Despite the robustness of radioligand binding assays, they carry inherent disadvantages in terms of safety precautions, expensive synthesis, special lab requirements, and waste dispos...

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Detalles Bibliográficos
Autores principales: Massink, A., Holzheimer, M., Hölscher, A., Louvel, J., Guo, D., Spijksma, G., Hankemeier, T., IJzerman, A. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648803/
https://www.ncbi.nlm.nih.gov/pubmed/26482925
http://dx.doi.org/10.1007/s11302-015-9477-0