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The role of aggrecan in normal and osteoarthritic cartilage
Aggrecan is a large proteoglycan bearing numerous chondroitin sulfate and keratan sulfate chains that endow articular cartilage with its ability to withstand compressive loads. It is present in the extracellular matrix in the form of proteoglycan aggregates, in which many aggrecan molecules interact...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648834/ https://www.ncbi.nlm.nih.gov/pubmed/26914753 http://dx.doi.org/10.1186/s40634-014-0008-7 |