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The role of aggrecan in normal and osteoarthritic cartilage

Aggrecan is a large proteoglycan bearing numerous chondroitin sulfate and keratan sulfate chains that endow articular cartilage with its ability to withstand compressive loads. It is present in the extracellular matrix in the form of proteoglycan aggregates, in which many aggrecan molecules interact...

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Detalles Bibliográficos
Autores principales: Roughley, Peter J, Mort, John S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648834/
https://www.ncbi.nlm.nih.gov/pubmed/26914753
http://dx.doi.org/10.1186/s40634-014-0008-7