Effects of mTOR inhibitors and cytoskeletal-directed agents alone and in combination against normal and neoplastic hematopoietic cells in vitro

The mechanistic target of rapamycin (mTOR) controls cell growth and enlargement and has been found to be aberrant in a wide variety of malignancies. Although mTOR is already an attractive antineoplastic target, overexpression or aberrant expression of mTOR may also provide an opportunity to further...

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Detalles Bibliográficos
Autores principales: Trendowski, Matthew, Christen, Timothy D., Andonova, Antoaneta A., Narampanawe, Berlini, Thibaud, Ashlee, Kusang, Tenzin, Fondy, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Preclinical Studies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648964/
https://www.ncbi.nlm.nih.gov/pubmed/26490657
http://dx.doi.org/10.1007/s10637-015-0294-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4648964/
https://www.ncbi.nlm.nih.gov/pubmed/26490657
http://dx.doi.org/10.1007/s10637-015-0294-7

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