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Impaired Contextual Fear Extinction Learning is Associated with Aberrant Regulation of CHD-Type Chromatin Remodeling Factors

Successful attenuation of fearful memories is a cognitive process requiring initiation of highly coordinated transcription programs. Chromatin-modulating mechanisms such as DNA methylation and histone modifications, including acetylation, are key regulators of these processes. However, knowledge con...

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Detalles Bibliográficos
Autores principales: Wille, Alexandra, Maurer, Verena, Piatti, Paolo, Whittle, Nigel, Rieder, Dietmar, Singewald, Nicolas, Lusser, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649039/
https://www.ncbi.nlm.nih.gov/pubmed/26635563
http://dx.doi.org/10.3389/fnbeh.2015.00313