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Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens
Cytotoxic T cells recognize, via their T cell receptors (TCRs), small antigenic peptides presented by the major histocompatibility complex (pMHC) on the surface of professional antigen-presenting cells and infected or malignant cells. The efficiency of T cell triggering critically depends on TCR bin...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649060/ https://www.ncbi.nlm.nih.gov/pubmed/26635796 http://dx.doi.org/10.3389/fimmu.2015.00582 |