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Identifying Individual T Cell Receptors of Optimal Avidity for Tumor Antigens

Cytotoxic T cells recognize, via their T cell receptors (TCRs), small antigenic peptides presented by the major histocompatibility complex (pMHC) on the surface of professional antigen-presenting cells and infected or malignant cells. The efficiency of T cell triggering critically depends on TCR bin...

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Detalles Bibliográficos
Autores principales:	Hebeisen, Michael, Allard, Mathilde, Gannon, Philippe O., Schmidt, Julien, Speiser, Daniel E., Rufer, Nathalie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649060/ https://www.ncbi.nlm.nih.gov/pubmed/26635796 http://dx.doi.org/10.3389/fimmu.2015.00582

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