Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids

The recent development of 3D-liver stem cell cultures (hepatic organoids) opens up new avenues for gene and/or stem cell therapy to treat liver disease. To test safety and efficacy, a relevant large animal model is essential but not yet established. Because of its shared pathologies and disease path...

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Detalles Bibliográficos
Autores principales: Nantasanti, Sathidpak, Spee, Bart, Kruitwagen, Hedwig S., Chen, Chen, Geijsen, Niels, Oosterhoff, Loes A., van Wolferen, Monique E., Pelaez, Nicolas, Fieten, Hille, Wubbolts, Richard W., Grinwis, Guy C., Chan, Jefferson, Huch, Meritxell, Vries, Robert R.G., Clevers, Hans, de Bruin, Alain, Rothuizen, Jan, Penning, Louis C., Schotanus, Baukje A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649105/
https://www.ncbi.nlm.nih.gov/pubmed/26455412
http://dx.doi.org/10.1016/j.stemcr.2015.09.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649105/
https://www.ncbi.nlm.nih.gov/pubmed/26455412
http://dx.doi.org/10.1016/j.stemcr.2015.09.002

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