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MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation
The molecules and mechanisms pertinent to the low immunogenicity of undifferentiated embryonic stem cells (ESCs) remain poorly understood. Here, we provide evidence that milk fat globule epidermal growth factor 8 (MFG-E8) is a vital mediator in this phenomenon and directly suppresses T cell immune r...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649138/ https://www.ncbi.nlm.nih.gov/pubmed/26455415 http://dx.doi.org/10.1016/j.stemcr.2015.09.005 |