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MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation

The molecules and mechanisms pertinent to the low immunogenicity of undifferentiated embryonic stem cells (ESCs) remain poorly understood. Here, we provide evidence that milk fat globule epidermal growth factor 8 (MFG-E8) is a vital mediator in this phenomenon and directly suppresses T cell immune r...

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Detalles Bibliográficos
Autores principales: Tan, Yuan, AlKhamees, Bodour, Jia, Deyong, Li, Li, Couture, Jean-François, Figeys, Daniel, Jinushi, Masahisa, Wang, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649138/
https://www.ncbi.nlm.nih.gov/pubmed/26455415
http://dx.doi.org/10.1016/j.stemcr.2015.09.005