Cargando…
MFG-E8 Is Critical for Embryonic Stem Cell-Mediated T Cell Immunomodulation
The molecules and mechanisms pertinent to the low immunogenicity of undifferentiated embryonic stem cells (ESCs) remain poorly understood. Here, we provide evidence that milk fat globule epidermal growth factor 8 (MFG-E8) is a vital mediator in this phenomenon and directly suppresses T cell immune r...
Autores principales: | Tan, Yuan, AlKhamees, Bodour, Jia, Deyong, Li, Li, Couture, Jean-François, Figeys, Daniel, Jinushi, Masahisa, Wang, Lisheng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649138/ https://www.ncbi.nlm.nih.gov/pubmed/26455415 http://dx.doi.org/10.1016/j.stemcr.2015.09.005 |
Ejemplares similares
-
Embryonic Stem Cell-Derived Factors Inhibit T Effector Activation and Induce T Regulatory Cells by Suppressing PKC-θ Activation
por: Mohib, Kanishka, et al.
Publicado: (2012) -
MFG-E8 Regulates the Immunogenic Potential of Dendritic Cells Primed with Necrotic Cell-Mediated Inflammatory Signals
por: Baghdadi, Muhammad, et al.
Publicado: (2012) -
B cell responses to apoptotic cells in MFG-E8-/- mice
por: Peng, YuFeng
Publicado: (2018) -
Essential Role of MFG-E8 for Phagocytic Properties of Microglial Cells
por: Liu, Yong, et al.
Publicado: (2013) -
Neurogenesis in Neurodegenerative Diseases: Role of MFG-E8
por: Cheyuo, Cletus, et al.
Publicado: (2019)