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ESC-Derived Basal Forebrain Cholinergic Neurons Ameliorate the Cognitive Symptoms Associated with Alzheimer’s Disease in Mouse Models

Degeneration of basal forebrain cholinergic neurons (BFCNs) is associated with cognitive impairments of Alzheimer’s disease (AD), implying that BFCNs hold potentials in exploring stem cell-based replacement therapy for AD. However, studies on derivation of BFCNs from embryonic stem cells (ESCs) are...

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Detalles Bibliográficos
Autores principales: Yue, Wei, Li, Yuanyuan, Zhang, Ting, Jiang, Man, Qian, Yun, Zhang, Min, Sheng, Nengyin, Feng, Su, Tang, Ke, Yu, Xiang, Shu, Yousheng, Yue, Chunmei, Jing, Naihe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649256/
https://www.ncbi.nlm.nih.gov/pubmed/26489896
http://dx.doi.org/10.1016/j.stemcr.2015.09.010