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Stroma-Derived Connective Tissue Growth Factor Maintains Cell Cycle Progression and Repopulation Activity of Hematopoietic Stem Cells In Vitro

Hematopoietic stem cells (HSCs) are preserved in co-cultures with UG26-1B6 stromal cells or their conditioned medium. We performed a genome-wide study of gene expression changes of UG26-1B6 stromal cells in contact with Lineage(−) SCA-1(+) KIT(+) (LSK) cells. This analysis identified connective tiss...

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Detalles Bibliográficos
Autores principales: Istvánffy, Rouzanna, Vilne, Baiba, Schreck, Christina, Ruf, Franziska, Pagel, Charlotta, Grziwok, Sandra, Henkel, Lynette, Prazeres da Costa, Olivia, Berndt, Johannes, Stümpflen, Volker, Götze, Katharina S., Schiemann, Matthias, Peschel, Christian, Mewes, Hans-Werner, Oostendorp, Robert A.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649380/
https://www.ncbi.nlm.nih.gov/pubmed/26527384
http://dx.doi.org/10.1016/j.stemcr.2015.09.018