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Structural basis of Sorcin-mediated calcium-dependent signal transduction
Sorcin is an essential penta-EF hand calcium binding protein, able to confer the multi-drug resistance phenotype to drug-sensitive cancer cells and to reduce Endoplasmic Reticulum stress and cell death. Sorcin silencing blocks cell cycle progression in mitosis and induces cell death by triggering ap...
Autores principales: | Ilari, Andrea, Fiorillo, Annarita, Poser, Elena, Lalioti, Vasiliki S., Sundell, Gustav N., Ivarsson, Ylva, Genovese, Ilaria, Colotti, Gianni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649501/ https://www.ncbi.nlm.nih.gov/pubmed/26577048 http://dx.doi.org/10.1038/srep16828 |
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